The morbidity and mortality of COVID-19 are correlated with the Ile105Val glutathione S-transferase P1 polymorphism

Egyptian Journal of Medical Human Genetics

Table 2 Multivariable linear regression analysis for associations of log-mortality and log-prevalence of COVID-19 with the frequency of the Val105 allele in the various countries around the world

Variables	Unstandardized coefficients		Standardized coefficients beta	Partial correlations	t	P
	B	Std. Error
Log-prevalence as dependent variable
Constant	− 1.067	1.231	-	-	− 0.867	0.391
Log-GNI per capita	0.815	0.262	0.407	0.424	3.034	0.004
Val105 allelic frequency	0.020	0.009	0.281	0.308	2.094	0.042
Log-mortality as dependent variable
Constant	− 3.2348	1.648	-	-	− 1.971	0.055
Log-GNI per capita	0.918	0.359	0.350	0.367	2.553	0.014
Val105 allelic frequency	0.027	0.013	0.296	0.316	2.156	0.037

The first model was significant with F = 6.76; df = 2, 42; P = 0.003; adjusted R² = 0.207. The second model was significant with F = 5.55; df = 2, 42; P = 0.007; adjusted R² = 0.171