The morbidity and mortality of COVID-19 are correlated with the Ile105Val glutathione S-transferase P1 polymorphism

Egyptian Journal of Medical Human Genetics

Table 4 Multivariable linear regression analysis for associations of log-mortality and log-prevalence of COVID-19 with the frequency of the Val105 allele in the various countries around the world in selected countries with GNI-per capita more than $15,000

Variables	Unstandardized coefficients		Standardized coefficients beta	Partial correlations	t	P
	B	Std. Error
Log-prevalence as dependent variable
Constant	− 4.790	1.717	-	-	− 2.789	0.009
Log-test	0.429	0.194	0.319	0.374	2.209	0.035
Log-GNI per capita	1.118	0.417	0.384	0.440	2.681	0.012
Val105 allelic frequency	0.028	0.010	0.360	0.456	2.806	0.009
Log-mortality as dependent variable
Constant	− 5.979	2.463	-	-	− 2.427	0.021
Log-GNI per capita	1.344	0.530	0.358	0.415	2.537	0.016
Val105 allelic frequency	0.051	0.014	0.509	0.544	3.606	0.001

The first model was significant with F = 10.726; df = 3, 30; P < 0.001; adjusted R² = 0.469. The second model was significant with F = 9.63; df = 2, 31; P < 0.001; adjusted R² = 0.344