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Table 6 Genotype and allele frequencies of IL12B (1188 A/C) and IL17A (−197G/A) polymorphisms in patients and controls

From: Role of interleukins 12B and 17A genetic variation in house dust mites allergy

The studied parameter

Controls N = 60

Patients N = 60

Fisher exact test

p value

(%)

(%)

IL-12B (+1188 A/C)

Genotype

 

 AA

54(90.0)

18 (30)

14.344

.008**

 AC

6 (10.0)

40 (66.7)

  

 CC

0 (0.0)

2 (3.3)

Allele

 A

114 (95.0)

76 (63.3)

11.574

.010**

 C

6 (5.0)

44 (36.7)

IL17A (−197G/A)

Genotype

 

 GG

48(80.0)

16 (26.7)

  

 GA

6(10.0)

38 (63.3)

12.192

.029*

 AA

6(10.0)

6 (10.0)

Allele

 G

102 (85.0)

70 (58.3)

16.4

.005**

 A

18 (15.0)

50 (41.7)

  1. Polymorphism is represented as number and percent. *p value ≤ 0.05 significant while **p value ≤ 0.01 highly significant