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Table 6 Genotype and allele frequencies of IL12B (1188 A/C) and IL17A (−197G/A) polymorphisms in patients and controls

From: Role of interleukins 12B and 17A genetic variation in house dust mites allergy

The studied parameter Controls N = 60 Patients N = 60 Fisher exact test p value
(%) (%)
IL-12B (+1188 A/C) Genotype  
 AA 54(90.0) 18 (30) 14.344 .008**
 AC 6 (10.0) 40 (66.7)   
 CC 0 (0.0) 2 (3.3)
Allele
 A 114 (95.0) 76 (63.3) 11.574 .010**
 C 6 (5.0) 44 (36.7)
IL17A (−197G/A) Genotype  
 GG 48(80.0) 16 (26.7)   
 GA 6(10.0) 38 (63.3) 12.192 .029*
 AA 6(10.0) 6 (10.0)
Allele
 G 102 (85.0) 70 (58.3) 16.4 .005**
 A 18 (15.0) 50 (41.7)
  1. Polymorphism is represented as number and percent. *p value ≤ 0.05 significant while **p value ≤ 0.01 highly significant