From: Role of interleukins 12B and 17A genetic variation in house dust mites allergy
The studied parameter | Controls N = 60 | Patients N = 60 | Fisher exact test | p value | |
---|---|---|---|---|---|
(%) | (%) | ||||
IL-12B (+1188 A/C) | Genotype | Â | |||
 AA | 54(90.0) | 18 (30) | 14.344 | .008** | |
 AC | 6 (10.0) | 40 (66.7) |  |  | |
 CC | 0 (0.0) | 2 (3.3) | |||
Allele | |||||
 A | 114 (95.0) | 76 (63.3) | 11.574 | .010** | |
 C | 6 (5.0) | 44 (36.7) | |||
IL17A (−197G/A) | Genotype |  | |||
 GG | 48(80.0) | 16 (26.7) |  |  | |
 GA | 6(10.0) | 38 (63.3) | 12.192 | .029* | |
 AA | 6(10.0) | 6 (10.0) | |||
Allele | |||||
 G | 102 (85.0) | 70 (58.3) | 16.4 | .005** | |
 A | 18 (15.0) | 50 (41.7) |