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Table 7 Genotype and allele frequencies of IL12B (+1188 A/C) and IL17A (−197G/A) polymorphisms among studied groups

From: Role of interleukins 12B and 17A genetic variation in house dust mites allergy

The studied parameter Controls
N = 60 (%)
Asthma
N = 20 (%)
AR
N = 20 (%)
Dermatitis N = 20 (%)
IL12B
(+1188 A/C)
Genotype
 AA 54 (90.0) 6 (30.0) 8 (40.0) 4(20.0)
 AC 6 (10.0) 14 (70.0) 10 (50.0) 16 (80.0)
 CC 0 (0.0) 0 (0.0) 2 (10 .0) 0 (0.0)
p value   .020* < .001** .005**
Allele
 A 114 (95.0) 26 (65.0) 26 (65.0) 24 (60.0)
 C 6 (5.0) 14 (35.0) 14 (35.0) 16 (40.0)
p value   .043* .043* .019*
IL17
(−197G/A)
Genotyping
 GG 48(80.0) 8 (40.0) 4 (20.0) 4(20.0)
 GA 6 (10.0) 12(60.0) 12(60.0) 14(70.0)
 AA 6 (10.0) 0 (0.0) 4(20.0) 2(10.0)
p value   .057 < .001** < .001**
Allele
 G 102 (85.0) 28 (70.0) 20 (50.0) 22 (55.0)
 A 18 (15.0) 12 (30.0) 20 (50.0) 18 (45.0)
p value   .450 .018* .038*
  1. Fisher exact test was used. All parameters represented as number and percent. *p value ≤ 0.05 significant while **p value ≤ 0.01 highly significant and p > 0.05 non-significant