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Egyptian Journal of Medical Human Genetics

Table 11 rs11536858 and rs1927914 allele combination distribution between cases and control

From: The association between toll-like receptor 4 (TLR4) genotyping and the risk of epilepsy in children

Haplotype combination

Control

N = 400 (%)

Cases

N = 664 (%)

Test of significance

Bonferroni correction

CG

74 (18.5)

162 (82.2)

p = 0.02*

p = 0.01*

CA

62 (15.5)

244 (36.8)

p < 0.001*

p = 0.001*

TG

138 (34.5)

88 (13.3)

p < 0.001*

p = 0.001*

TA

126 (31.5)

170 (25.6)

p = 0.03*

p = 0.015*

  1. There is a statistically significant difference between cases and control regarding all combinations with the highest combination frequency among cases being CG (82.2%) and then CA (36.8%)
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