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Egyptian Journal of Medical Human Genetics

Table 2 rs1927914 genotype genetic polymorphism distribution between cases and control

From: The association between toll-like receptor 4 (TLR4) genotyping and the risk of epilepsy in children

Genotype

rs1927914

Total number

n = 133

Studied groups

χ2

p value

OR (95% CI)

Control

n = 50 (%)

Cases

n = 83 (%)

CC

63

8 (12.7)

55 (87.3)

39.9

< 0.001*

15.3 (6.05–38.6)

CT

12

2 (16.7)

10 (83.3)

11.3

0.007*

11.1 (2.21–55.9)

TT (r)

58

40 (69.0)

18 (31.0)

  

1

HW equilibrium

< 0.001*

< 0.001*

   
  1. Significant association has been found as the homozygous CC genotype is more at risk for developing epilepsy than homozygous TT by 15.3 (p value < 0.001* and OR 15.3). The heterozygous CT genotype is more at risk for developing epilepsy than TT by 11.1 (p value 0.007* and OR 11.1)
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