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Egyptian Journal of Medical Human Genetics

Table 4 Association between TLR genetic polymorphism rs1927914 and epilepsy type

From: The association between toll-like receptor 4 (TLR4) genotyping and the risk of epilepsy in children

Genotype

rs1927914

Total cases

n = 83

Epilepsy type

χ2

p

OR (95% CI)

 

Primary

n = 61 (%)

Secondary

n = 22 (%)

CC

55

39 (70.9)

16 (29.1)

10.5

0.001*

6.3 (1.9–20.7)

CT

10

9 (90.0)

1 (10.0)

1.21

0.27

0.29 (0.03–2.9)

TT (r)

18

13 (72.2)

5 (27.8)

  

1

HW equilibrium

< 0.001*

< 0.001*

   
  1. Significant association was detected as p value 0.001*; cases with CC genotype are more at risk for developing primary epilepsy than TT cases by 6.3 times (OR = 6.3)
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