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Table 4 Allele and genotype frequencies of HLA-G 14-bp insertion/deletion polymorphism in healthy populations from Iraq and other countries

From: Susceptibility role of soluble HLA-G and HLA-G 14-bp insertion/deletion polymorphism in inflammatory bowel disease

Country

N

HLA-G 14-bp allele

HLA-G 14-bp genotype

HWE p

Reference

Ins

Del

Ins/Ins

Ins/Del

Del/Del

Iraq

100

82 (41.0)

118 (59.0)

20 (20.0)

42 (42.0)

38 (38.0)

0.187

Present study

Algeria

100

77 (38.5)

123 (61.5)

15 (15.0)

47 (47.0)

38 (38.0)

0.940

[22]

Brazil

120

107 (44.6)

133 (55.4)

26 (21.7)

55 (45.8)

39 (32.5)

0.427

[23]

China

292

193 (33.1)

391(66.9)

35 (12.0)

123 (42.1)

134 (45.9)

0.411

[24]

Egypt

100

120 (60.0)

80 (40.0)

38 (38.0)

44 (44.0)

18 (18.0)

0.401

[25]

Greece

192

176 (45.8)

208 (54.2)

39 (20.3)

98 (51.0)

55 (28.7)

0.698

[26]

India

383

347 (45.3)

419 (54.7)

86 (22.4)

175 (45.7)

122 (31.9)

0.127

[27]

Iran

210

180 (42.9)

240 (57.1)

52 (24.8)

76 (36.2)

82 (39.0)

< 0.001

[28]

Italy

451

351 (38.9)

551 (61.1)

65 (14.4)

221 (49.0)

165 (36.6)

0.514

[29]

Japan

777

389 (25.0)

1165 (75.0)

58 (7.5)

273 (35.1)

446 (57.4)

0.075

[30]

Korea

491

232 (23.6)

750 (76.4)

17 (3.5)

198 (40.3)

276 (56.2)

0.009

[31]

Mexico

214

195 (45.6)

233 (54.4)

41 (19.2)

113 (52.8)

60 (28.0)

0.346

[32]

Poland

465

385 (41.4)

545 (58.6)

77 (16.5)

231(49.7)

157 (33.8)

0.607

[33]

Saudi Arabia

119

117 (49.2)

121 (50.8)

27 (22.7)

63 (52.9)

29 (24.4)

0.519

[34]

Spain

33

17 (25.8)

49 (74.2)

2 (6.1)

13 (39.4)

18 (54.5)

0.863

[35]

Tunisia

170

174 (51.2)

166 (48.8)

42 (24.7)

90 (52.9)

38 (22.4)

0.439

[36]

Turkey

191

188 (49.2)

194 (50.8)

48 (25.1)

92 (48.2)

51 (26.7)

0.615

[37]

p

 

< 0.001

 

< 0.001

    
  1. Significant p is bold-marked
  2. Ins insertion, Del deletion, HWE Hardy-Weinberg equilibrium, p Pearson’s chi-squared test probability