Genetic model | Allele/Genotype | HC (N = 100) | IBD (N = 100) | UC (N = 50) | CD (N = 50) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
N (%) | N (%) | OR (95% CI) | p (pc) | N (%) | OR (95% CI) | p (pc) | N (%) | OR (95% CI) | p (pc) | ||
Allele | Ins | 82 (41.0) | 53 (26.5) | Reference | 28 (28.0) | Reference | 25 (25.0) | Reference | |||
Del | 118 (59.0) | 147 (73.5) | 1.93 (1.27–2.94) | 0.003 (0.018) | 72 (72.0) | 1.79 (1.07–3.00) | 0.031 (NS) | 75 (75.0) | 2.08 (1.23–3.54) | 0.007 (0.042) | |
Recessive | Del/Del | 38 (38.0) | 54 (54.0) | Reference | 27 (54.0) | Reference | 27 (54.0) | Reference | |||
Ins/Del + Ins/Ins | 62 (62.0) | 46 (46.0) | 1.92 (1.09–3.37) | 0.024 (NS) | 23 (46.0) | 1.92 (0.96–3.81) | 0.064 (NS) | 23 (46.0) | 1.92 (0.96–3.81) | 0.064 (NS) | |
Dominant | Ins/Ins | 20 (20.0) | 7 (7.0) | Reference | 5 (10.0) | Reference | 2 (4.0) | Reference | |||
Ins/Del + Del/Del | 80 (80.0) | 93 (93.0) | 3.32 (1.34–8.26) | 0.010 (NS) | 45 (90.0) | 2.25 (0.79–6.40) | 0.129 (NS) | 48 (96.0) | 6.00 (1.34–26.81) | 0.019 (NS) | |
Overdominant | Ins/Del | 42 (42.0) | 39 (39.0) | Reference | 18 (36.0) | Reference | 21 (42.0) | Reference | |||
Ins/Ins + Del/Del | 58 (58.0) | 61 (61.0) | 1.13 (0.64–1.99) | 0.666 (NS) | 32 (64.0) | 1.29 (0.64–2.60) | 0.408 (NS) | 29 (58.0) | 1.00 (0.50–1.99) | 1.000 (NS) | |
Codominant | Ins/Ins | 20 (20.0) | 7 (7.0) | Reference | 5 (10.0) | Reference | 2 (4.0) | Reference | |||
Ins/Del | 42 (42.0) | 39 (39.0) | 2.65 (1.01–6.96) | 0.047 (NS) | 18 (36.0) | 7.11 (1.53–32.98) | 0.012 (NS) | 21 (42.0) | 5.00 (1.07–23.44) | 0.041 (NS) | |
Del/Del | 38 (38.0) | 54 (54.0) | 4.06 (1.56–10.56) | 0.004 (0.024) | 27 (54.0) | 2.84 (0.95–8.51) | 0.062 (NS) | 27 (54.0) | 1.71 (0.56–5.28) | 0.384 (NS) | |
HWE-p | 0.187 | 0.991 | 0.449 | 0.396 |