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Table 2 Drug-likeness properties of ten top compounds

From: Structure-based design of some quinazoline derivatives as epidermal growth factor receptor inhibitors

Molecule MW TPSA WLOGP No. of H-bond donors No of H-bond acceptors RO5 violations
Molecule 3 501.46 114.47 4.44 3 9 1
Molecule 5 534.97 94.6 4.11 2 7 1
Molecule 6 500.52 94.6 4.46 2 7 1
Molecule 7 517.96 107.49 4.95 2 7 1
Molecule 9 400.43 85.37 3.54 2 5 0
Molecule 12 428.84 85.37 4.69 2 6 0
Molecule 22 557.62 97.84 4.39 2 8 1
Molecule 29 526 88.61 4.16 2 7 1
Molecule 34 560.04 124.89 4.61 2 8 1
Molecule 43 441.52 79.38 3.85 2 5 0