Table 3 ADME properties of ten top compounds
Molecule | GI absorption | BBB permeant | Pgp substrate | Bioavailability score | Synthetic accessibility |
|---|---|---|---|---|---|
Molecule 3 | Low | No | No | 0.55 | 3.54 |
Molecule 5 | Low | No | Yes | 0.55 | 4.18 |
Molecule 6 | High | No | Yes | 0.55 | 4.11 |
Molecule 7 | High | No | Yes | 0.55 | 4.16 |
Molecule 9 | High | No | No | 0.55 | 3.67 |
Molecule 12 | High | No | No | 0.55 | 3.58 |
Molecule 22 | High | No | Yes | 0.55 | 4.63 |
Molecule 29 | High | No | Yes | 0.55 | 4.32 |
Molecule 34 | Low | No | Yes | 0.55 | 4.67 |
Molecule 43 | High | No | Yes | 0.55 | 3.48 |