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Egyptian Journal of Medical Human Genetics
Fig. 1 | Egyptian Journal of Medical Human Genetics

Fig. 1

From: Dysregulation in growth arrest-specific 5 and metastasis-associated lung adenocarcinoma transcript 1 gene expression predicts diagnosis and renal fibrosis in systemic lupus erythematosus patients

Fig. 1

The relative expression of GAS5 and MALAT1 between SLE patients and controls a MALAT1 relative expression between SLE groups versus controls. MALAT1 expression is significantly higher in SLE patients compared to control group (p = < 0.001). b GAS5 relative expression between SLE groups versus controls. GAS5 expression was significantly lower than the control group (p = < 0.001). c MALAT1 relative expression between two SLE subgroups, nephritis, and non-nephritis versus controls showed a significant difference in LN and NN patients compared to control cases (p = < 0.001). However, there were no statistically significant differences in LN patients compared to NN (p = 0.25). d GAS5 relative expression between the two SLE subgroups, nephritis, and non-nephritis versus controls showed a significant difference in LN patients compared to control groups (p = < 0.001). In addition, GAS5 showed significant downregulation in LN patients compared to NN patients (p = 0.003). Red, SLE cases; blue, control group; yellow, NN; green, LN; p, p value. The central box in the diagram represents the lower and upper quartiles (IQR). The central horizontal line in the box represents the median

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