Table 1 Some genetic variants associated with particular disease outcomes in specific viral infections
From: Understanding the genetic determinant of severity in viral diseases: a case of SARS-Cov-2 infection
Viral infections (condition) | Associated gene variants | Disease outcome |
|---|---|---|
Influenza virus (severe pneumonitis) | IRF7, IRF9, TLR3, IFITM3, SFPA/B | |
Rhinovirus (severe pneumonitis) | IFN1 | Susceptibility [7] |
Human immunodeficiency virus | CCR5, HLAB57 | |
Herpes simplex virus (encephalitis) | TLR3, TRIF, TRAF3, IRF3, TBK1 | |
Norovirus and rotavirus | FUT2 | |
Respiratory syncytial virus (bronchiolitis) | IL4, IL4RA, IL8, IL10, IL13, SFPA/D |