Skip to main content

Table 3 Biomarkers fold change in the studied groups

From: Long non-coding RNA HOTAIR and HOTTIP as potential biomarkers for hepatitis C virus genotype 4-induced hepatocellular carcinoma

BiomarkersControl
n = 25
Group I
(CLD without HCC)
n = 50
Group II
CLD with HCC
n = 25
Subgroup Ia
(CLD without cirrhosis)
n = 25
Subgroup Ib
(CLD with cirrhosis)
n = 25
Fold-changeType of RegulationFold-changeType of RegulationFold-changeType of Regulation
HOTAIR14.1536Up10.724Up20.508Up
HOTTIP13.9372Up11.46Up22.788Up
  1. The fold change results depend on the fold change low: fold-change (2^(−Delta Delta Ct)) is the normalized gene expression (2^(−Delta Ct)) in the test sample divided the normalized gene expression (2^(−Delta Ct)) in the control sample. (Fold-change values less than 1 indicate a negative or downregulation https://www.biostars.org/))