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Table 3 Biomarkers fold change in the studied groups

From: Long non-coding RNA HOTAIR and HOTTIP as potential biomarkers for hepatitis C virus genotype 4-induced hepatocellular carcinoma

Biomarkers

Control

n = 25

Group I

(CLD without HCC)

n = 50

Group II

CLD with HCC

n = 25

Subgroup Ia

(CLD without cirrhosis)

n = 25

Subgroup Ib

(CLD with cirrhosis)

n = 25

Fold-change

Type of Regulation

Fold-change

Type of Regulation

Fold-change

Type of Regulation

HOTAIR

1

4.1536

Up

10.724

Up

20.508

Up

HOTTIP

1

3.9372

Up

11.46

Up

22.788

Up

  1. The fold change results depend on the fold change low: fold-change (2^(−Delta Delta Ct)) is the normalized gene expression (2^(−Delta Ct)) in the test sample divided the normalized gene expression (2^(−Delta Ct)) in the control sample. (Fold-change values less than 1 indicate a negative or downregulation https://www.biostars.org/))