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Egyptian Journal of Medical Human Genetics

Table 5 Correlation study of the studied genes

From: Long non-coding RNA HOTAIR and HOTTIP as potential biomarkers for hepatitis C virus genotype 4-induced hepatocellular carcinoma

 

HOTAIR

HOTTIP

 

Correlation coefficient

Sig.

(2-tailed)

Correlation coefficient

Sig.

(2-tailed)

HOTAIR

  

0.652**‡

0.001

HOTTIP

0.652**‡

0.001

  

Age

0.231*‡

0.044

0.202

0.078

Sex

−0.211

0.065

−0.221

0.054

AFP

0.481**‡

0.001

0.400**‡

0.001

Albumin

−0.304**‡

0.007

−0.392**‡

0.001

T. bil

0.116

0.316

0.133

0.248

D. bil

0.164

0.154

0.123

0.286

ALT

0.394**‡

0.001

0.228*‡

0.046

AST

0.200

0.081

0.188

0.102

ALP

0.402**‡

0.001

0.452**‡

0.001

UREA

0.227*‡

0.047

0.307**‡

0.007

CREAT

0.187

0.103

0.222

0.052

PT

0.483**‡

0.001

0.458**‡

0.001

PC

−0.411**‡

0.001

−0.306**‡

0.007

INR

0.379**‡

0.001

0.340**‡

0.002

HB

−0.172

0.135

−0.200

0.08

WBCs

0.104

0.369

0.175

0.128

Platelets

−0.418**‡

0.001

−0.330**‡

0.003

  1. All parametric parameters were analyzed by Pearson’s correlation test, while all nonparametric parameters were analyzed by Spearman rho (rank correlation)
  2. ‡(r) Initial is calculated regarding Pearson’s correlation test
  3. Results of correlation studies depending on the correlation coefficient values (r) as follows: weak < 0.24; fair 0.25–0.49; moderate 0.5–0.74; strong 0.75–1
  4. Alkaline phosphates (ALP), hemoglobin (HB), white blood cells (WBCs), ultrasound (U/S), alanine aminotrasferase (ALT), aspartate aminotransferase (AST), alpha-fetoprotein (AFP), total bilirubin (T.Bil), direct bilirubin (D.Bil), prothrombin time (PT), prothrombin concentration (PC) and international normalized ratio (INR)
  5. *Correlation is significant at the 0.05 level (2-tailed)
  6. **Correlation is significant at the 0.01 level (2-tailed)
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