Table 1 Characteristics of studies included in meta-analysis
Serial no. | Author | Year | Country | Ethnicity | Clinical subtype | Gender wise distribution | Mean age | Mean BMI | SOC | Sample size | Genotyping | HWE | NOS score | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cases [N] | Controls [N] | |||||||||||||
1 | Larifla et al. | 2017 | French West Indies islands | Afro-Caribbeans | CAD | 64.1%/35.9% = M/F | 63.51 | 27.4 | HB | 234 | 520 | TaqMan | Y | 8 |
2 | Abd El-Aziz | 2016 | Egypt | Egyptians | CAD | 60.6% = M 39.4% = F | 44.5 | 102 ≥ 25 | PB | 132 | 135 | Multi-AMRS | Y | 7 |
3 | Afroze et al. | 2015 | India | Caucasians | CAD | 130 = M 70 = F | 153 ≥ 50 | 108 ≥ 25 | PB | 200 | 450 | PCR-RFLP | Y | 8 |
4 | Atis et al. | 2016 | Turkey | Caucasians | CAD | 50/50 = M/F | 59.68 | 29.617 | HB | 100 | 100 | Kit in Roche light cycler apparatus and hybridization probes | Y | 8 |
5 | Cheema et al. | 2015 | Pakistan | Caucasians | CAD | 22.3% = F 77.7% = M | 54 | 28.98 | HB | 508 | 183 | TaqMan | Y | 8 |
6 | Long et al. | 2019 | China | Chinese han | CAD | 67.4%/32.6% = M/F | 64.05 | 30.85 | HB | 406 | 231 | Real time PCR and sanger sequencing | Y | 9 |
7 | Ghaznavi | 2018 | Iran | Caucasians | CAD | 103/97 = M/F | 60.2 | PB | 200 | 200 | PCR-RFLP | Y | 8 | |
8 | Arafa et al. | 2018 | Egypt | Egyptians | CHD | 85/15 = M/F | 55 | PB | 100 | 100 | PCR-RFLP | Y | 8 | |
9 | Heidari | 2013 | Iran | Caucasians | CAD | 35%/65% = M/F | 52.5 | 25.4 | PB | 66 | 61 | PCR-RFLP | Y | 7 |
10 | Hou et al. | 2020 | China | Asian | CAD | F | 68.16 | PB | 653 | 646 | PCR, Hybridization to sinochip | Y | 9 | |
11 | Souza et al. | 2007 | Brazilian | Caucasian | CAD | 128/72 = M/F | 60.8 | HB | 100 | 100 | PCR-RFLP | Y | 8 | |
12 | Djan et al. | 2011 | Serbian | Caucasian | CAD | 30/0 = M/F | 29.2 | PB | 30 | 30 | PCR-RFLP | Y | 7 | |