Fig. 4

a Protein modeling for normal and mutated CNTNAP2 protein product with marked mutation and conformational change highlighted in a box. The mutated protein structure was rendered as non-functional with reduced stability and depth and increased solvent accessibility. b Domain boundary prediction to understand the changes in residues and aligned termini profile. The coil residue have undergone multiple changes highlighted with an asterisk in the graph across normal and mutated protein leading to disorder and variation