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Table 2 Comparison between IPF patients and control groups regarding pulmonary function tests, UIP pattern in HRCT, and relative expression of TERRA mRNA

From: Telomeric repeat-containing ribonucleic acid (TERRA) expression in patients with idiopathic pulmonary fibrosis

Variables

IPF patient group (n_30)

Control group (n_30)

Test of significance

P-value

FEV1 %predicted

79.91 ± 10.13

84.71 ± 10.60

t = 1.79

0.078

FVC% predicted

72.87 ± 9.73

94.42 ± 10.41

t = 8.27

≤ 0.001*

DLCO%

 Median (min-max)

55.0 (26–89)

94.0 (70–110)

Z = 9.75

≤ 0.001*

HRCT reticular extent score

2.00 (1.00–4.00)

0.00 (0.00–1.00)

Z = 10.66

≤ 0.001*

HRCT honeycombing extent score

2.00 (0.00–4.00)

0.00 (0.00–1.00)

Z = 8.94

≤ 0.001*

HRCT GGOs extent score

0.00 (0.00–2.00)

0.00 (0.00–1.00)

Z = 2.13

0.033*

Relative expression

1.99 ± 0.63

0.97 ± 0.12

t = 8.68

≤ 0.001*

  1. t Student t-test, Z Mann-Whitney test
  2. *Significant p < 0.05