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Table 3 Risk estimate for AML in the two studied genes

From: Impact of Cytochromes P450 3A4 and 2B6 gene polymorphisms on predisposition and prognosis of acute myeloid leukemia: an Egyptian case-control study

 

AML

Control

OR

95% CI

p-value

CYP2B6 gene polymorphism

 GG

23 (46%)

36 (72%)

3.0

1.3-6.9

0.008

 GT + TT

27 (54%)

14 (28%)

CYP3A4 gene polymorphism

 AA

31 (62%)

43 (86%)

3.8

1.4-10.1

0.006

 AG + GG

19 (38%)

7 (14%)

CYP2B6 gene polymorphism + CYP3A4 gene polymorphism

 Combined

14 (43.7%)

1 (5.0%)

14.8

1.8-124.2

0.003

 Single

18 (56.3%)

19 (95.0%)

  1. OR odds ratio, CI confidence interval