Skip to main content

Table 3 Risk estimate for AML in the two studied genes

From: Impact of Cytochromes P450 3A4 and 2B6 gene polymorphisms on predisposition and prognosis of acute myeloid leukemia: an Egyptian case-control study

  AML Control OR 95% CI p-value
CYP2B6 gene polymorphism
 GG 23 (46%) 36 (72%) 3.0 1.3-6.9 0.008
 GT + TT 27 (54%) 14 (28%)
CYP3A4 gene polymorphism
 AA 31 (62%) 43 (86%) 3.8 1.4-10.1 0.006
 AG + GG 19 (38%) 7 (14%)
CYP2B6 gene polymorphism + CYP3A4 gene polymorphism
 Combined 14 (43.7%) 1 (5.0%) 14.8 1.8-124.2 0.003
 Single 18 (56.3%) 19 (95.0%)
  1. OR odds ratio, CI confidence interval