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Table 4 Relation of CYP2B6 gene polymorphism and CYP3A4 gene polymorphism with demographic, clinical and laboratory data in AML patients

From: Impact of Cytochromes P450 3A4 and 2B6 gene polymorphisms on predisposition and prognosis of acute myeloid leukemia: an Egyptian case-control study

  CYP2B6 gene polymorphism CYP3A4 gene polymorphism
Wild Hetero + Homo p value Wild Hetero + Homo p value
Median Age (years) 32.4 37.6 0.379 35.4 40.1 0.418
Sex, No (%)
 Male 14 (48.2%) 15 (51.8%) 0.704 19 (65.5%) 10 (34.5%) 0.547
 Female 9 (42.8%) 12 (57.2%) 12 (57.1%) 9 (42.9%)  
Splenomegaly, No. (%) 15 (55.5%) 12 (44.5%) 0.141 17 (63.0%) 10 (37.0%) 0.879
Hepatomegaly, No. (%) 12(54.5%) 10 (45.5%) 0.282 14(63.6%) 8(36.4%) 0.833
Hemoglobin (g/dL) 7.5 ± 1.4 7.9 ± 2.0 0.476 7.8 ± 1.9 8.1 ± 1.9 0.535
Median TLC (×103/mm3) 42.8 56.4 0.722 60.3 53.4 0.542
Median Platelet count (×103/mm3) 68.4 50.8 0.784 78.6 66.4 0.810