Table 5 Relation between cytogenetic risk stratification and CYP gene mutations
Favorable (cytogenetic) (n = 14) | Intermediate + poor (cytogenetic) (n = 36) | P value | OR (95%CI) | |
|---|---|---|---|---|
CYP2B6 | ||||
Wild (GG) | 9 (64.3%) | 14 (18.5%) | 0.106 | 2.8 (0.8-10.2) |
Mutant (GT + TT) | 5 (35.7%) | 22 (81.5%) | ||
CYP3A4 | ||||
Wild (AA) | 12 (85.7%) | 19 (52.8%) | 0.031 | 5.4 (1.0-27.5) |
Mutant (AG + GG) | 2 (14.3%) | 17 (47.2%) | ||