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Table 5 Relation between cytogenetic risk stratification and CYP gene mutations

From: Impact of Cytochromes P450 3A4 and 2B6 gene polymorphisms on predisposition and prognosis of acute myeloid leukemia: an Egyptian case-control study

  Favorable (cytogenetic) (n = 14) Intermediate + poor (cytogenetic) (n = 36) P value OR (95%CI)
CYP2B6
 Wild (GG) 9 (64.3%) 14 (18.5%) 0.106 2.8 (0.8-10.2)
 Mutant (GT + TT) 5 (35.7%) 22 (81.5%)
CYP3A4
 Wild (AA) 12 (85.7%) 19 (52.8%) 0.031 5.4 (1.0-27.5)
 Mutant (AG + GG) 2 (14.3%) 17 (47.2%)
  1. OR odds ratio, CI confidence interval