Table 3 Distribution of ABCC8 (rs1799854) genotype and allelic frequencies in diabetic children compared to controls
From: Association of ABCC8 and KCNJ11 gene variants with type 1 diabetes in south Indians
Inheritance model | Genotype | Diabetes n=60 n (%) | Controls n=60 n (%) | p value |
|---|---|---|---|---|
Co dominant | C/C | 13 (21.7%) | 26 (43.3%) | <0.012* 0.274 |
C/T | 30 (50%) | 16 (26.7%) | ||
T/T | 17 (28.3%) | 18 (30%) | ||
Dominant | C/C | 13 (21.7%) | 26 (43.3%) | <0.011* |
C/T-T/T | 47 (78.3%) | 34 (56.7%) | ||
Recessive | C/C-C/T | 43 (71.7%) | 42 (70%) | 0.84 |
T/T | 17 (28.3%) | 18 (30%) | ||
Over dominant | C/C-T/T | 30 (50%) | 44 (73.3%) | <0.008* |
C/T | 30 (50%) | 16 (26.7%) | ||
Allele frequencies | C | 56(46.4%) | 68(56.6%) | |
T | 64(53.3%) | 52(43.3%) | 0.15 |