Table 4 Distribution of ABCC8 (rs 1801261) genotype and allelic frequencies in diabetic children compared to controls
From: Association of ABCC8 and KCNJ11 gene variants with type 1 diabetes in south Indians
Inheritance model | Genotype | Diabetes n=60 n (%) | Controls n=60 n (%) | OR (95% CI) | p value |
|---|---|---|---|---|---|
Co dominant | C/C | 24 (40%) | 22 (36.7%) | 1.00 | 0.36 0.82 |
C/T | 16 (26.7%) | 23 (38.3%) | 0.64 (0.27–1.51) | ||
T/T | 20 (33.3%) | 15 (25%) | 1.22 (0.50–2.96) | ||
Dominant | C/C | 24 (40%) | 22 (36.7%) | 1.00 | 0.71 |
C/T-T/T | 36 (60%) | 38 (63.3%) | 0.87 (0.42–1.81) | ||
Recessive | C/C-C/T | 40 (66.7%) | 45 (75%) | 1.00 | 0.31 |
T/T | 20 (33.3%) | 15 (25%) | 1.50 (0.68–3.32) | ||
Over dominant | C/C-T/T | 44 (73.3%) | 37 (61.7%) | 1.00 | 0.17 |
C/T | 16 (26.7%) | 23 (38.3%) | 0.58 (0.27–1.27) | ||
Allele frequencies | C | 64 (53.3%) | 67 (55.8%) | ||
T | 56 (46.6%) | 53 (44.1%) | 1.106 (0.663–1.843) | 0.79 |