Table 5 Distribution of KCNJ11 (rs 5215) genotype and allelic frequencies in diabetic children compared to controls
From: Association of ABCC8 and KCNJ11 gene variants with type 1 diabetes in south Indians
Inheritance model | Genotype | Diabetes n=60 n (%) | Controls n=60 n (%) | OR (95% CI) | p value |
|---|---|---|---|---|---|
Co dominant | G/G | 33 (55%) | 38 (63.3%) | 1.00 | |
G/A | 11 (18.3%) | 12 (20%) | 1.06 (0.41–2.71) | 0.41 | |
A/A | 16 (26.7%) | 10 (16.7%) | 1.84 (0.74–4.61) | 0.27 | |
Dominant | G/G | 33 (55%) | 38 (63.3%) | 1.00 | 0.35 |
G/A-A/A | 27 (45%) | 22 (36.7%) | 1.41 (0.68–2.94) | ||
Recessive | G/G-G/A | 44 (73.3%) | 50 (83.3%) | 1.00 | 0.18 |
A/A | 16 (26.7%) | 10 (16.7%) | 1.82 (0.75–4.42) | ||
Over dominant | G/G-A/A | 49 (81.7%) | 48 (80%) | 1.00 | 0.82 |
G/A | 11 (18.3%) | 12 (20%) | 0.90 (0.36–2.23) | ||
Allele frequencies | G | 77 (64.1%) | 88 (73.3%) | 0.16 | |
A | 43 (35.8) | 32 (26.6%) | 1.533 (0.8838–2.675) |