MDR1 C3435T genotype | Drug | χ2 | p | OR (95%CI) |
---|
Resistance, n = 63 (%) | Responsive, n = 43 (%) |
---|
CC(r) | 32 (64.0) | 18 (36.0) | | | 1 |
CT | 21 (51.2) | 20 (48.8) | 1.5 | 0.2 | 0.6 (0.3–1.4) |
TT | 10 (66.7) | 5 (33.3) | 0.04 | 0.85 | 1.13 (0.33–3.8) |
- No statistically significant association was found between drug response or drug resistance, and MDR1 C3435Tgenotype distribution among epilepsy cases with 66.7% of TT genotype was detected among cases with drug resistance. The Hardy–Weinberg equation shows a non-statistically significant difference from the gene distribution in the total population
- χ2 chi-square test, OR odds ratio, p probability, HW Hardy–Weinberg equilibrium