Genetic polymorphism of HLA-G gene (G*01:03, G*01:04, and G*01:05N) in Iraqi patients with inflammatory bowel disease (ulcerative colitis and Crohn’s disease)

Egyptian Journal of Medical Human Genetics

Table 5 HLA-G01:04* and HLA-G01:05N* frequencies in inflammatory bowel disease patients classified according to demographic and clinical characteristics

Characteristic		N	HLA-G01:04* allele model				p	HLA-G01:05N* allele model				p
			Absent		Present			Absent		Present
			N	%	N	%		N	%	N	%
Gender	Male	56	19	33.9	37	66.1	0.672	49	87.5	7	12.5	0.075
Gender	Female	44	13	29.5	31	70.5		32	72.7	12	27.3
Cigarette-smoking	Smoker	75	25	33.3	50	66.7	0.805	64	85.3	11	14.7	0.077
Cigarette-smoking	Non-smoker	25	7	28.0	18	72.0		17	68.0	8	32.0
Family history	Yes	15	2	13.3	13	86.7	0.134	13	86.7	2	13.3	0.729
Family history	No	85	30	35.3	55	64.7		68	80.0	17	20.0
Abdominal/colon pain	Present	66	22	33.3	44	66.7	0.822	56	84.8	10	15.2	0.188
Abdominal/colon pain	Absent	34	10	29.4	24	70.6		25	73.5	9	26.5
Diarrhea	Present	56	19	33.9	37	66.1	0.672	49	87.5	7	12.5	0.075
Diarrhea	Absent	44	13	29.5	31	70.5		32	72.7	12	27.3
Fever	Present	49	14	28.6	35	71.4	0.524	42	85.7	7	14.3	0.310
Fever	Absent	51	18	35.3	33	64.7		39	76.5	12	23.5
Aphthous ulcer	Present	24	7	29.2	17	70.8	0.806	16	66.7	8	33.3	0.069
Aphthous ulcer	Absent	76	25	32.9	51	67.1		65	85.5	11	14.5
Arthralgia	Present	72	20	27.8	52	72.8	0.160	56	77.8	16	22.2	0.260
Arthralgia	Absent	28	12	42.9	16	57.1		25	89.3	3	10.7
Skin rash	Present	10	4	40.0	6	60.0	0.722	7	70.0	3	30.0	0.396
Skin rash	Absent	90	28	31.1	62	68.9		74	82.2	16	17.8
Appendectomy	Yes	13	3	23.1	10	76.9	0.541	11	84.6	2	15.4	1.000
Appendectomy	No	87	29	33.3	58	66.7		70	80.5	17	19.5
Bowel stricture	Present	7	2	28.6	5	71.4	1.000	6	85.7	1	14.3	1.000
Bowel stricture	Absent	93	30	32.32	63	67.7		75	80.6	18	19.4
Colostomy	Present	11	4	36.4	7	63.6	0.741	9	81.8	2	18.2	1.000
Colostomy	Absent	89	28	31.5	61	68.5		72	80.9	17	19.1
Fistula	Present	16	7	43.7	9	56.3	0.380	12	75.0	4	25.0	0.498
Fistula	Absent	84	25	29.8	59	70.2		69	82.1	15	17.9
Hemorrhoid	Present	9	3	33.3	6	66.7	1.000	6	66.7	3	33.3	0.366
Hemorrhoid	Absent	91	29	31.9	62	68.1		75	82.4	16	17.6