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Table 2 Analysis of the overlap of the cured genes with Hallmark annotated sets in MsigDB

From: Differential gene expression analysis of ankylosing spondylitis shows deregulation of the HLA-DRB, HLA-DQB, ITM2A, and CTLA4 genes

Gene set name

Description

Genes in Overlap (number, genes)

p-value

FDR q-value

IL2 STAT5 signaling

Genes upregulated by STAT5 in response to IL2 stimulation.

8: CCND3, IL2RB, IL2RA, TNFRSF9, TLA4, ICOS, ITGA6, EOMES

2.93e−8

1.47e−6

Allograft rejection

Genes upregulated during transplant rejection.

7: CCND3, IL2RB, IL2RA, CD2, ETS1, KLRD1, CD3E

5.69e−7

1.42e−5

Androgen response

Genes defining response to androgens.

5: CCND3, TNFAIP8, ELL2, ACTN1, KLK3

4.47e−6

7.45e−5

TNFA signaling via NF-kB

Genes regulated by NF-kB in response to TNF

4: CCND3, TNFRSF9, TNFAIP8, KLF10

1.4e−3

1.75e−2