Variables | Control group (n =40) | T2DM patients (n =60) | P value |
---|---|---|---|
Body mass index (kg/m2) | 22.18 ± 1.289 | 36.03 ± 4.26 | ˂0.001* |
Waist/hip ratio | 0.864 ± 0.121 | 1.17 ± 0.31 | ˂0.001* |
Systolic blood pressure | 117.5 ± 8.40 | 149.7 ± 20.54 | ˂0.001* |
Diastolic blood pressure | 75.6 ± 4.589 | 92.92 ± 14.33 | ˂0.001* |
Total cholesterol (mg/dl) | 184.3 ± 19.90 | 222.88 ± 28.1 | ˂0.001* |
Triglycerides (mg/dl) | 175.26 ± 31.019 | 276.16 ± 58.6 | ˂0.001* |
LDL cholesterol (mg/dl) | 100.08 ± 23.067 | 124.91 ± 32.4 | ˂0.001* |
HDL cholesterol (mg/dl) | 56.48 ± 4.87 | 35.25 ± 5.63 | ˂0.001* |
FPG (mg/dl) | 89.72 ± 6.304 | 220.97 ± 30.04 | ˂0.001* |
HbA1c (%) | 5.63 ± 0.624 | 9.59 ± 2.206 | ˂0.001* |
eGFR (mL/min) | 93.37 ± 7.56 | 76.19 ± 13.2 | ˂0.001* |
Serum creatinine (mg/dl) | 0.916 ± 0.27 | 1.46 ± 0.48 | ˂0.001* |
UACR (mg/g) | 20.72 ± 2.304 | 122.97 ± 103.04 | ˂0.001* |
Relative expression of circANKRD36 | 0.111 ± 0.013 | 0.219 ± 0.061 | ˂0.001* |
mRNA expression level of ANKRD36 | 0.0033 ± 0.004 | 0.006454 ± 0.0018 | ˂0.001* |