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Table 2 Anthropometric and biochemical characteristics of the studied groups

From: The expression profile of circANKRD36 and ANKRD36 as diagnostic biomarkers of chronic kidney disease in patients with type 2 diabetes mellitus

Variables

Control group (n =40)

T2DM patients (n =60)

P value

Body mass index (kg/m2)

22.18 ± 1.289

36.03 ± 4.26

˂0.001*

Waist/hip ratio

0.864 ± 0.121

1.17 ± 0.31

˂0.001*

Systolic blood pressure

117.5 ± 8.40

149.7 ± 20.54

˂0.001*

Diastolic blood pressure

75.6 ± 4.589

92.92 ± 14.33

˂0.001*

Total cholesterol (mg/dl)

184.3 ± 19.90

222.88 ± 28.1

˂0.001*

Triglycerides (mg/dl)

175.26 ± 31.019

276.16 ± 58.6

˂0.001*

LDL cholesterol (mg/dl)

100.08 ± 23.067

124.91 ± 32.4

˂0.001*

HDL cholesterol (mg/dl)

56.48 ± 4.87

35.25 ± 5.63

˂0.001*

FPG (mg/dl)

89.72 ± 6.304

220.97 ± 30.04

˂0.001*

HbA1c (%)

5.63 ± 0.624

9.59 ± 2.206

˂0.001*

eGFR (mL/min)

93.37 ± 7.56

76.19 ± 13.2

˂0.001*

Serum creatinine (mg/dl)

0.916 ± 0.27

1.46 ± 0.48

˂0.001*

UACR (mg/g)

20.72 ± 2.304

122.97 ± 103.04

˂0.001*

Relative expression of circANKRD36

0.111 ± 0.013

0.219 ± 0.061

˂0.001*

mRNA expression level of ANKRD36

0.0033 ± 0.004

0.006454 ± 0.0018

˂0.001*

  1. T2DM Type 2 diabetes mellitus, FPG Fasting plasma glucose, HbA1c Hemoglobin, A1c Estimated glomerular filtration rate, UACR Urine albumin: creatinine ratio, circANKRD36 Circular ankyrin repeat domain 36
  2. *P < 0.05