Variables | Normal (n=38) | Microalbuminuria (n=15) | Macroalbuminuria (n=7) | P1 | P2 | P3 |
---|---|---|---|---|---|---|
Duration of diabetes (years) | 8.864 ± 3.1 | 10.87 ± 3.31 | 15.17 ± 6. | ˂0.001* | ˂0.001* | ˂0.001* |
Body mass index (kg/m2) | 35.18 ± 1.289 | 37.4 ± 4.3 | 38.2 ± 4.26 | ˂0.001* | ˂0.001* | 0.891 |
Waist/hip ratio | 0.964 ± 0.121 | 1.27 ± 0.31 | 1.27 ± 0.31 | ˂0.001* | ˂0.001* | ˂0.001* |
Systolic blood pressure | 140.5 ± 8.43 | 145.7 ± 12.2 | 140.7 ± 14.3 | 0.878 | 0.943 | 0.970 |
Diastolic blood pressure | 85.6 ± 4.58 | 99.9 ± 14.3 | 105.9 ± 14.3 | ˂0.001* | ˂0.001* | 0.839 |
Total cholesterol (mg/dl) | 216.3 ± 19.9 | 232.8 ± 25.1 | 234.8 ± 48.1 | ˂0.001* | 0.128 | 0.914 |
Triglycerides (mg/dl) | 175.3 ± 31.1 | 266.4 ± 37.6 | 285.3 ± 44.6 | ˂0.001* | ˂0.001* | 0.800 |
LDL cholesterol (mg/dl) | 111.1 ± 26.2 | 114.5 ± 36.4 | 130.9 ± 37.4 | 0.093 | 0.135 | 0.824 |
HDL cholesterol (mg/dl) | 36.9 ± 4.87 | 32.25 ± 1.5 | 31.25 ± 3.4 | ˂0.001* | 0.055 | 0.694 |
FPG (mg/dl) | 227.1 ± 16.3 | 231.9 ± 31.4 | 265.9 ± 41.3 | 0.077 | 0.886 | 0.289 |
HbA1c (%) | 8.63 ± 1.4 | 9.59 ± 2.3 | 10.59 ± 1.5 | ˂0.001* | 0.222 | 0.447 |
eGFR (mL/min) | 93.37 ± 7.5 | 76.19 ± 13.2 | 76.19 ± 13.2 | ˂0.001* | 0.135 | 0.772 |
Serum creatinine (mg/dl) | 1.216 ± 0.27 | 1.46 ± 0.9 | 2.36 ± 1.2 | 0.250 | ˂0.001* | ˂0.001* |
UACR (mg/g) | 25.7 ± 3.3 | 183.97 ± 58.1 | 358.7 ± 94.3 | ˂0.001* | ˂0.001* | ˂0.001* |
Medication | ||||||
Diet | 8 (21.1%) | 7 (46.7%) | 6 (85.7%) | ˂0.001* | ˂0.001* | ˂0.001* |
Oral | 8 (21.1%) | 7 (46.7%) | 5 (71.4%) | ˂0.001* | ˂0.001* | ˂0.001* |
Insulin | 19 (50%) | 9 (60%) | 5 (71.4%) | ˂0.001* | ˂0.001* | ˂0.001* |
Vascular complications | ||||||
Retinopathy | 14 (36.8%) | 8 (53.3%) | 7 (100%) | ˂0.001* | ˂0.001* | ˂0.001* |
Neuropathy | 20 (52.6%) | 10 (66.7%) | 5 (71.4%) | ˂0.001* | ˂0.001* | ˂0.001* |
Stroke | 6 (15.8%) | 8 (53.3%) | 6 (85.7%) | ˂0.001* | ˂0.001* | ˂0.001* |
CHD | 14 (36.8%) | 8 (53.3%) | 7 (100%) | ˂0.001* | ˂0.001* | ˂0.001* |