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Table 1 Demographic and clinical data of the studied groups

From: Role of engulfment and cell motility 1 (ELMO1) gene polymorphism in development of diabetic kidney disease

Variables Group 1
(n=100)
Group 2
(n=102)
Group 3
(n=102)
p value Post hoc test
Age (years) -----------
 Mean ±SD 48.78 ± 5.00 47.88 ± 4.56 47.14± 6.38 0.097
 Median (IQR) 48 (46–51) 46.5 (46–51) 46.5 (43–54)  
Gender ------------
Male 64 (64.0%) 76 (74.5%) 66 (64.7%) 0.201
Female 36 (36.0%) 26 (25.5%) 36 (35.3%)  
Current smoking --------------
No 84 (84.0%) 88 (86.3%) 102 (100.0%) 0.015
Yes 16 (16.0%) 7 (13.7%) 0 (0.0%)  
Duration (years) ---------------
 Mean ±SD 7.98 ± 1.65 4.84 ± 1.24   <0.001
 Median (IQR) 8 (7–9) 5.0 (4–6) -----  
BMI (kg/m2) P1 0.204
 Mean ±SD 35.32 ± 2.8 34.64 ± 2.54 23.75 ± 0.90 <0.001 P2 <0.001
 Median (IQR) 35.07(33.3–36.96) 35.12 (33.03–36.41) 23.8 (23.18–24.51)   P3 <0.001
Waist circumference (cm) P1 0.058
 Mean ±SD 105.62 ± 5.70 103.94 ± 4.33 75.78 ± 2.77 <0.001 P2 <0.001
 Median (IQR) 107(104–109) 104 (101–106) 76 (74–78)   P3 <0.001
Waist/hip ratio P1 0.873
 Mean ±SD 0.87 ± 0.04 0.88 ± 0.04 0.78 ± 0.01 <0.001 P2 <0.001
 Median (IQR) 0.88 (0.86–0.90) 0.89 (0.84–0.90) 0.78 (0.77–0.79)   P3 <0.001
SBP (mmHg) P1 <0.001
 Mean ±SD 129.96 ± 7.16 121.72 ± 6.16 111.96 ± 8.62 <0.001 P2 <0.001
 Median (IQR) 130 (130–135) 120 (120–125) 110 (100–120)   P3 <0.001
DBP (mmHg) P1 <0.001
 Mean ±SD 85.74 ± 5.97 80.00 ± 4.89 74.50 ± 5.31 <0.001 P2 <0.001
 Median (IQR) 85 (80–90) 80 (80.0–82) 70 (70–80)   P3 <0.001
  1. Group 1 DKD patients, Group 2 diabetic patients without DKD, Group 3 healthy controls, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, P1 group 1 vs group 2, P2 group 1 vs group 3, P3 group 2 vs group 3. Statistically significant at p ≤ 0.05