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Table 4 Genotype and allelic frequency for VDR polymorphism at FokI (rs2228570 C > T)

From: Vitamin D levels and vitamin D receptor genetic variants in Egyptian cardiovascular disease patients with and without diabetes

rs2228570 (FokI)

Group A

(n=120)

Group B

(n=124)

Group C

(n= 69)

Group D

(n=69)

P values

Genotype

 CC

36 (30.0%)

44 (35.5%)

36 (52.2%)

42 (60.9%)

Ë‚0.001

 CT

58 (48.3%)

56 (45.2%)

30 (43.5%)

21 (30.4%)

 TT

26 (21.7%)

24 (19.4%)

3 (4.3%)

6 (8.7%)

 CT+TT

84 (70%)

80 (64.6%)

33 (47.8%)

27 (39.1%)

Ë‚0.001

P value

0.001b*

0.654c

0.002a*

0.654c

0.218 a

  

Hardly Weinberg equilibrium test p value

0.77

0.41

0.28

0.17

 

Allele

 C

130 (54.2%)

144 (58.1)

102 (73.9%)

105 (76.1%)

Ë‚0.001

 T

110 (45.8%)

104 (41.9%)

36 (26.1%)

33 (23.9%)

P value

<0.001b*

0.386c

<0.001a*

0.301a

  

OR (95% CI)

2.397 (1.518-3.786)b

1.172 (0.819-1.676)c

2.298 (1.443-3.660)

1.42 (0.79-2.54)

  
  1. Chi-square (χ2) test was used to get the statistical variation. a, significant difference from group D; b, significant difference from group C; c, significant difference from group B