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Table 5 Genotype and allele frequency for VDR polymorphism at BsmI (rs1544410 A >G)

From: Vitamin D levels and vitamin D receptor genetic variants in Egyptian cardiovascular disease patients with and without diabetes

rs1544410 (BsmI)

Group A

(n=120)

Group B

(n=124)

Group C

(n= 69)

Group D

(n=69)

P values

Genotype

 AA

10 (8.3%)

16 (12.9%)

24 (34.8%)

36 (52.2%)

Ë‚0.001

 AG

35 (29.0%)

44 (35.5%)

39 (56.5%)

27 (39.1%)

 GG

75 (62.7%)

64 (51.6%)

6 (8.7%)

6 (8.7%)

 AG+GG

110 (91.7%)

108 (87.1%)

45 (65.2%)

33 (47.8%)

Ë‚0.001

P value

<0.001b*

0.057c

<0.001a*

0.101a

  

Hardly Weinberg equilibrium test p value

0.056

0.065

0.07

0.77

 

Allele

 A

55 (22.4%)

76 (31.0%)

87 (63.8%)

99 (73.2%)

Ë‚0.001

 G

185 (77.6%)

172 (69.0%)

51 (36.2%)

39 (26.8%)

P value

<0.001b*

0.013c*

<0.001a*

0.06a

  

OR (95% CI)

6.482 (4.07-10.32)b

1.679 (1.11-2.53)c

5.745 (3.63-9.08)

1.55 (0.929-2.58)

  
  1. Chi-square (χ2) test was used to get the statistical variation. a, significant difference from group D; b, significant difference from group C; c, significant difference from group B