Table 3 Correlation of HOTAIR gene expression to AML patient’s clinicopathological parameters
From: Study of HOTAIR LncRNA in AML patients in context to FLT3-ITD and NPM1 mutations status
Expression | Sig. | ||
|---|---|---|---|
Low | High | ||
Gender | |||
Male | 12 | 14 | 0.671 |
Female | 11 | 10 | |
Age | |||
< 50 | 13 | 20 | 0.046 |
≥ 50 | 10 | 4 | |
TLC | |||
< 50 | 12 | 20 | 0.022 |
≥ 50 | 11 | 4 | |
HB | |||
< 8 | 13 | 3 | 0.001 |
≥ 8 | 10 | 21 | |
PLT | |||
< 50 | 12 | 14 | 0.34 |
≥ 50 | 11 | 10 | |
Wild-FLT3 | |||
Wild NPM1 | 9 | 13 | 0.017 |
Mutant NPM1 | 5 | 0 | |
FLT3-ITD | |||
Wild NPM1 | 6 | 8 | 0.9 |
Mutant NPM1 | 2 | 3 | |
CR | |||
Achieved | 8 | 10 | 0.318 |
Failed | 15 | 14 | |
Blasts | |||
< 50 | 11 | 6 | 0.104 |
≥ 50 | 12 | 18 | |
FAB | |||
M2-M4 | 8 | 10 | 0.627 |
Others | 11 | 12 | |