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Table 4 Combined effect of HOTAIR and mutation analysis on CR and poor outcome

From: Study of HOTAIR LncRNA in AML patients in context to FLT3-ITD and NPM1 mutations status

 

CR

Outcome

CR

%

Poor

%

Low expression

 NPM1-WT/FLT3WT

4/9

44%

7/9

89%

 NPM1-mut/FLT3-mut

2/2

100%

2/2

100

 NPM1-mut/FLT3-WT

1/5

20%

5/5

100%

 NPM1-WT/FLT3-mut

1/6

16%

5/6

84%

High expression

 NPM1-WT/FLT3-WT

4/13

38%

10/13

62%

 NPM1-mut/FLT3-mut

1/3

33%

3/3

100%

 NPM1-WT/FLT-mut

5/8

63%

3/8

37.5