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Egyptian Journal of Medical Human Genetics

Table 5 Multivariate analysis of the association of the genetic variance of NAMPT rs4730153 with MetS and modifying factors for subjects aged ≤ 45 years

From: A genetic variant of the NAMPT gene rs4730153 as a risk factor for the metabolic syndrome in younger age: a single-centre pilot study in Yogyakarta, Indonesia

rs4730153 for age ≤ 45

Logistic regression model

B

SE

p-value

Adjusted OR (95% CI)

Genotype

    

 Additive model

    

  AA

  

ref

 

  GA

  

NS

 

  GG

2.78

1.34

0.039

16.14 (1.16–225.21)

 Recessive/dominant model

    

  AA

  

ref

 

  GG+GA

2.35

1.19

0.048

10.52 (1.02–108.01)

  AA+GA

  

ref

 

  GG

1.36

0.63

0.031

3.88 (1.13–13.33)

 Allele

    

  A allele

  

ref

4.19

  G allele

1.43

0.52

0.006

(1.51–11.64)

  1. Hosmer and Lemeshow test was performed to analyse the goodness of fit; p-value for all models was > 0.05. Logistic regression model inserting obesity, hypercholesterolemia, smoking and food intake as modifiers. B logistic regression model coefficient, NS non-significant, SE standard error, OR odds ratio with 95% CI, ref reference genotype
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