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Fig. 1 | Egyptian Journal of Medical Human Genetics

Fig. 1

From: Chanarin–Dorfman syndrome: clinical/genetic features and natural history in six Pakistani patients

Fig. 1

Liver histology and Jordan’s anomaly in a CDS patient (case 2). (a) Liver parenchyma (H&E) shows distorted lobular architecture and expanded portal areas. Trichrome stain reveals portal and periportal fibrosis along with many thin fibrous septa suggestive of steatohepatitis with fibrosis. (b) Higher magnification shows hepatocytes are enlarged with compressed sinusoids and severe pan lobular steatosis. (c) Microphotographs of May–Grünwald–Giemsa buffy coats showing Jordan’s anomaly

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