Fig. 4From: Chanarin–Dorfman syndrome: clinical/genetic features and natural history in six Pakistani patientsa Phylogenetic tree shows the conservation of Abhd5 protein in other orthologs (across different species).The evolutionary history was inferred using the Neighbor–Joining method [1]. The optimal tree with the sum of branch length = 1.01547038 is shown. The evolutionary distances were computed using the Poisson correction method. b Multiple sequence alignment of Abhd5 protein showing high conservation of amino acids across the mutated region of c.730–731insA (p.Thr244Asnfs*10) variation among different species. Mutation position marked in black boxBack to article page