Fig. 5

KOG Functional Classification Analysis of total markers among the subjects. Information Storage and processing: J-Translation, ribosomal structure and biogenesis, A-RNA processing and modification, K-Transcription, L-Replication, recombination and repair, B-Chromatin structure and dynamics. Cellular processing and signaling: D-Cell cycle control, cell division, and chromosome partitioning, Y-Nuclear structure, V-Defense mechanisms, T-Signal transduction mechanisms, M-Cell wall/membrane/envelope biogenesis, N-Cell motility, Z-Cytoskeleton, W-Extracellular structures, U-Intracellular trafficking, secretion, and vesicular transport, O-Posttranslational modification, protein turnover, chaperones. Metabolism: C-Energy production and conversion, G-Carbohydrate transport and metabolism, E-Amino acid transport and metabolism, F-Nucleotide transport and metabolism, H-Coenzyme transport and metabolism, I-Lipid transport and metabolism, P-Inorganic ion transport and metabolism, Q-Secondary metabolites biosynthesis, transport and catabolism. Poorly characterized: R-General function prediction only, S-Function unknown