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Table 2 The most significant variant retrieved from Manhattan Plot

From: Screening of single nucleotide polymorphisms among fuchs’ endothelial corneal dystrophy subjects in Malaysia

Single nucleotide polymorphism

rs11626651 (exm2272196)

Gene symbol

LOC105370676

Chromosome

14

Position (base pair)

101,717,022

Minor allele

A

Number of cases with minor allele (n = 12)

11 (91.67%)

Number of controls with minor allele (n = 12)

3 (25%)

Frequency of allele (cases)

0.8333

Frequency of allele (controls)

0.1667

Chi-square

21.33

p value

3.86 × 10−6

 − log10 p value

5.41

Odds ratio (confidence interval)

25 (5.478–114.1)

  1. p-value < 5 × 10−6