Table 3 Association of candidate genes with FECD
Chromosome number | Gene | SNPs | Position (base pair) | Minor allele | Major allele | Chi square | p-value* | Odds ratio (OR) |
|---|---|---|---|---|---|---|---|---|
1 | COL8A2 | rs96067 | 36106319 | G | A | 0.7513 | 0.3861 | 0.6044 |
1 | COL8A2 | rs142956038 | 36110260 | G | A | 0.3556 | 0.551 | 0.4783 |
1 | COL8A2 | rs274776 | 36121728 | A | G | 0.1355 | 0.7128 | 1.25 |
10 | ZEB1/TCF8 | rs431073 | 31388277 | C | A | 1.917 | 0.1662 | 0 |
10 | ZEB1/TCF8 | rs74905658 | 31399430 | A | G | 0.3556 | 0.551 | 0.4783 |
10 | ZEB1/TCF8 | rs187774661 | 31405487 | C | A | 1.021 | 0.3122 | 0 |
10 | ZEB1/TCF8 | rs112139244 | 31415097 | A | G | 3.501 | 0.06133 | 0 |
18 | TCF4 | rs77452859 | 55320989 | A | G | 0.3556 | 0.551 | 2.091 |
18 | TCF4 | rs9966430 | 55458133 | C | A | 1.422 | 0.233 | 2.055 |
18 | TCF4 | rs9636107 | 55532886 | A | G | 0.5053 | 0.4772 | 0.6 |
20 | SLC4A11 | rs797045107 | 3234173 | C | A | 0.08466 | 0.7711 | 0.8442 |