Screening of single nucleotide polymorphisms among fuchs’ endothelial corneal dystrophy subjects in Malaysia

Egyptian Journal of Medical Human Genetics

Table 4 Associations of candidate genes in various populations

First Author (year)	Country	Ethnicity	Study design	Genotyping method	Case/Control	SNP	Gene	Association
Baratz et al.,2010 [20]	USA	Caucasian	GWAS	Taqman assay	130/260	rs613872	TCF4	*
Thalamuthu et al.,2011 [44]	Singapore	Asian	Case–control	MassArray	57/121	rs613872	TCF4	**
Wieben et al., 2014 [47]	USA	Caucasian	Case–control	Sequencing	68/16	rs613872	TCF4	*
Nanda et al., 2014 [45]	India	Asian	Case–control	Sequencing	44/108	rs613872	TCF4	**
Hemadevi et al., 2010 [13]	India	Asian	Case–control	Sequencing	80/100	Several SNPs	COL8A2, SLC4A11	**
Kobayashi et al., 2004 [46]	Japan	Asian	Case–control	Sequencing	15/36	R155Q and T502M	COL8A2	**
Mehta et al., 2008 [43]	Chinese	Asian	Case–control	Sequencing	74/93	Asn696Ser	TCF8	**
Current study	Malaysia	Malaysian	GWAS	Global screening array	12/12	rs11626651	LINC02320	*