Association between PON1 rs662 gene polymorphism and serum paraoxonase1 level in coronary artery disease patients in Northern India

Egyptian Journal of Medical Human Genetics

Table 1 Demographic, clinical, and biochemical characteristics of the study population

Variable	CAD (n = 71)	Control (n = 71)	P value
Age (years)	56.5 ± 10.80	50.17 ± 9.50	0.09
Males, %	74.6	60.6	0.29
Hypertension, %	49.3	43.7	0.50
DM, %	38.0	28.2	0.21
Smokers, %	39.4	22.5	0.03
Family history,%	65.1	34.9	0.02
Lipid lowering Drugs, %	18.3	14.1	0.49
BMI > 25 kg/m², %	51.6	48.4	0.59
TC, mg/dL	123.79 ± 43.25	129.48 ± 30.48	0.36
LDL-C, mg/dL	78.24 ± 30.78	74.38 ± 21.49	0.39
HDL-C, mg/dL	31.01 ± 7.10	40.51 ± 7.01	< 0.001
TG, mg/dL	130.72 ± 66.37	125.85 ± 39.44	0.59
AIP	0.603 ± 0.183	0.476 ± 0.144	< 0.001
CK (U/L)	228.35 ± 402.99	76.99 ± 61.32	0.003
CKMB (U/L)	34.55 ± 45.04	14.93 ± 17.02	0.001

Values are expressed as mean ± standard deviation or percentage
DM diabetes mellitus, BMI body mass index, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglycerides, AIP atherogenic index of plasma (AIP=log10 (TG/HDL-C), CK creatine kinase