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Table 8 Studies showing the association of PON1 Q192R polymorphism in distinct ethnic groups

From: Association between PON1 rs662 gene polymorphism and serum paraoxonase1 level in coronary artery disease patients in Northern India

 

Title of study

Population

Association with CAD

1

Coronary artery disease and the frequencies of MTHFR and PON1 gene polymorphism studies in a varied population of Hyderabad, Telangana region, in South India [17]

South India

R allele

2

The Q192R polymorphism of the paraoxonase 1 gene is a risk factor for coronary artery disease in Saudi subjects [18]

Saudi

R allele

3

Association between PON1 rs662 polymorphism and coronary artery disease [19]

China

R allele

4

Paraoxonase 1 (PON1) activity, but not PON1 (Q192R) phenotype is a predictor of coronary artery disease in a middle-aged Serbian population [20]

Serbia

No association

5

Deshpande CS, Singhal RS, Mukherjee MS. Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk [21]

Asian Indian Women

R allele

6

Association of paraoxonase-1 Q192R (rs662) single nucleotide variation with cardiovascular risk in coffee harvesters of Central Colombia [22]

Central Colombia

Q allele

7

The Gln-Arg192 polymorphism of human paraoxonase gene is not associated with coronary artery disease in Italian patients [23]

Italy

No association