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Table 1 Spontaneous apoptosis indices, MCL1, BCL2, BCL-XL gene expression in cases and controls

From: Spontaneous apoptosis and BCL2 gene expression as predictors of early death and short overall survival in acute leukemia patients: a prospective, case cohort study

 

Control

AML

ALL

P

Post hoc test*

Annexine V

1.1 (0.1–1.5)

4.2 (0.3–13.6)

14.3 (2.2–18.6)

 < 0.001

Control versus ALL < 0.00

AML versus ALL < 0.001

Control versus AML < 0.001

Anexine&PI†

0.3 (0.1–0.9)

5.3 (0.6–17.1)

11.6 (5.9–24.1)

 < 0.001

Total apoptosis

1.6 (0.3–1.9)

9.7 (1.7–19.3)

22.6 (14.8–38.0)

 < 0.001

MCL1

1.7 (0.2–2.9)

2.0 (0.2–17.1)

3.2 (0.1–8.9)

NS

 

BCL2

0.8 (0.2–4.4)

2.4 (0–29.7)

3.9 (0.2–16.6)

NS

 

BCL-XL

0.7 (0.3–5.4)

2.0 (0–9.2)

3.1 (0.0–6.3)

NS

 
  1. Results are expressed as medians and ranges. Kruskal–wallis tests with Dunn–Bonferroni post hoc method were applied
  2. *Results of the post hoc test were the same for all apoptosis indices
  3. †Propidium Iodide
  4. Significant P values are written in bold; NS, not significant