| |
Annxine V
|
P
|
Annexine&PI
|
P
|
Total apoptosis
|
P
|
|---|
|
AML patients (n = 70)
|
|
FAB
|
|
APL* (n = 11)
|
4.2 (0.3–6.2)
|
NS
|
5.4 (0.9–7.8)
|
NS
|
6.3 (3.1–13.3)
|
NS
|
|
Non-APL (n = 59)
|
4.3 (0.3–13.6)
|
5.3 (0.6–17.1)
|
9.8 (1.7–19.3)
|
|
Performance status
|
|
0/1 (n = 33)
|
5.2 (0.3–9.5)
|
NS
|
5.5 (0.6–14.6)
|
NS
|
12.3 (2.9–18.5)
|
NS
|
|
2/3 (n = 37)
|
3.9 (1.0–13.6)
|
4.1 (0.6–17.2)
|
9.6 (1.7–19.3)
|
|
Early death†
|
|
Yes (n = 20)
|
3.8 (1.0–6.9)
|
NS
|
3.4 (0.7–7.6)
|
0.006
|
8.8 (1.7–12.5)
|
0.001
|
|
No (n = 48)
|
4.5 (0.3–13.6)
|
5.6 (0.6–17.1)
|
12.4 (2.9–19.3)
|
|
ALL patients (n = 28)
|
|
FAB
|
|
B.ALL (n = 16)
|
9.1 (2.2–15.9)
|
0.001
|
13.4 (11.3–24.1)
|
0.001
|
21.8 (14.8–38.0)
|
NS
|
|
T.ALL (n = 12)
|
15.9 (13.8–18.6)
|
7.7 (5.9–9.1)
|
23.8 (20.5–27.4)
|
|
Performance status
|
|
0/1 (n = 18)
|
15.4 (13.5–18.6)
|
0.001
|
8.3 (5.9–24.1)
|
NS
|
25.5 (20.5–38.0)
|
0.001
|
|
2/3 (n = 10)
|
6.3 (2.2–9.3)
|
12.7 (11.3–13.8)
|
19.2 (14.8–22.4)
|
|
Early death
|
|
Yes (n = 5)
|
3.7 (3.1–8.5)
|
0.001
|
12.7 (11.3–13.1)
|
NS
|
15.8 (14.8–22.3)
|
0.002
|
|
No (n = 23)
|
14.6 (2.2–18.6)
|
9.1 (5.9–24.1)
|
24.0 (14.9–38.0)
|
- *Acute Promyelocytic Leukemia
- †Two patients left hospital at the induction phase
- Mann–Whitney’s U test was used
- Significant P values are written in bold; NS, not significant
