Egyptian Journal of Medical Human Genetics

Table 4 Univariate and multivariate analyses of prognostic factors for overall survival in non-APL patients

From: Spontaneous apoptosis and BCL2 gene expression as predictors of early death and short overall survival in acute leukemia patients: a prospective, case cohort study

Prognostic factors	Univariate analysis		Multivariate analysis
Prognostic factors	Hazard Ratio (95% CI)	P	Hazard Ratio (95% CI)	P
Performance status	186 (2.5–140)	0.004	15.6 (2.1–118)	0.008
Total apoptosis	5.8 (1.9–17.9)	0.002	4.7 (1.5–14.4)	0.007
BCL2	0.2 (0.08–0.6)	0.001	0.3(0.1–0.7)	0.01
Age	2.1 (0.7–6.6)	0.2
Gender	0.5 (0.2–1.5)	0.2
Cytogenetics	0.6 (0.3–1.4)	0.3
TLC*	1.7 (0.5–5.1)	0.3
MCL1	0.9 (0.3–2.8)	0.9
BCL-XL	0.9 (0.3–2.8)	0.9

*Total leukocytes count
Significant P values are written in bold

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