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Table 4 Univariate and multivariate analyses of prognostic factors for overall survival in non-APL patients

From: Spontaneous apoptosis and BCL2 gene expression as predictors of early death and short overall survival in acute leukemia patients: a prospective, case cohort study

Prognostic factors Univariate analysis Multivariate analysis
Hazard Ratio (95% CI) P Hazard Ratio (95% CI) P
Performance status 186 (2.5–140) 0.004 15.6 (2.1–118) 0.008
Total apoptosis 5.8 (1.9–17.9) 0.002 4.7 (1.5–14.4) 0.007
BCL2 0.2 (0.08–0.6) 0.001 0.3(0.1–0.7) 0.01
Age 2.1 (0.7–6.6) 0.2   
Gender 0.5 (0.2–1.5) 0.2   
Cytogenetics 0.6 (0.3–1.4) 0.3   
TLC* 1.7 (0.5–5.1) 0.3   
MCL1 0.9 (0.3–2.8) 0.9   
BCL-XL 0.9 (0.3–2.8) 0.9   
  1. *Total leukocytes count
  2. Significant P values are written in bold