Characteristics | T2DM patients with DN (N = 140) | T2DM patients without DN (N = 140) | Control (N = 140) | P value |
---|---|---|---|---|
Gender (Male:Female) | 75:65 | 62:78 | 60:80 | 0.91 |
Age (years) | 56.2 ± 5.7 | 55.5 ± 6.6 | 55.1 ± 6.8 | 0.44 |
BMI (kg/m2) | 24.0 ± 4.1 | 24.0 ± 3.4 | 24.2 ± 3.5 | 0.56 |
Diabetes duration (years) | ||||
3–5 years | 38 | 32 | – | |
5–10 years | 34(11.4 ± 4.0) | 46 (11 ± 3.8) | – | 0.45 |
> 10 years | 68 | 62 | – | |
Fasting blood glucose (mg/dL) | 156.0 ± 12.7 | 151.1 ± 4.3 | 87.9 ± 8.9 | < 0.001 |
Postprandial glucose (mg/dL) | 171.3 ± 53.3 | 164.8 ± 42.7 | 118.9 ± 12.3 | < 0.001 |
HbA1c (%) | 9.0 ± 2.2 | 8.9 ± 1.9 | 7.8 ± 2.0 | 0.68 |
Protein-to-creatinine ratio ( mg/g) | 62.8 ± 5.7 | 54.3 ± 2.5 | 32.4 ± 1.23 | < 0.001 |
Serum creatinine (mg/dL) | 2.80 ± 2.7 | 0.9 ± 0.24 | 0.8 ± 0.15 | < 0.001 |
HDL (mg/dl) | 64.1 ± 15.9 | 61.05 ± 18.08 | 49 ± 15.7 | 0.08 |
LDL (mg/dl) | 97.2 ± 29.2 | 95.1 ± 30.3 | 93.6 ± 31.0 | 0.96 |
eGFR (ml/min) | 55 ± 13.1 | 101.1 ± 12.3 | 130.8 ± 16.0 | < 0.001 |
SBP (mmHg) | 145.7 ± 5.5 | 135.08 ± 7.1 | 113 ± 7.3 | < 0.001 |
DBP (mmHg) | 104.8 ± 4.9 | 90.3 ± 5.2 | 75.2 ± 5.4 | < 0.001 |