Table 4 Association of eNOS and TGF-β1 gene polymorphisms in T2DM patients with DN and controls

Co dominant model

GG

71

82

1.00

–

GT

36

42

0.80 (0.47–1.36)

0.42

TT

33

16

2.39 (1.24–4.58)

0.008*

eNOS

(rs1799983)

Dominant model- GT + TT vs GG

76

64

1.41 (0.88–2.25)

0.15

Recessive model-TT vs GG + GT

86

67

1.73 (1.07–2.79)

0.02*

Allelic model

Allele G

177

225

1.00

–

Allele T

103

55

0.42(0.28–0.61)

0.0001*

Co dominant model

GG

85

79

1.00

–

GC

29

32

0.88 (0.49–1.55)

0.66

CC

26

29

0.87 (0.48–1.57)

0.65

TGF-β1

(rs1800471)

Dominant model-GC + CC vs GG

76

83

0.81 (0.50–1.30)

0.39

Recessive model-CC vs GG + GC

62

74

0.70 (0.44–1.13)

0.15

Allelic model

Allele G

180

171

1.00

–

Allele C

100

109

1.14 (0.81–1.61)

0.43