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Table 6 Logistic regression analysis for the association among diabetic nephropaathy, genetic polymorphisms and potential risk factors in type 2 diabetes patients

From: Role of eNOS and TGFβ1 gene polymorphisms in the development of diabetic nephropathy in type 2 diabetic patients in South Indian population

Variables

Odds ratio

95% CI

P value

Age

1.03

0.43–1.08

0.94

Diabetes duration (years)

1.32

0.67–2.26

0.01*

BMI

0.76

0.23–0.98

0.57

FBG (mg/dl)

1.26

0.63–2.02

0.35

PPG(mg/dl)

1.22

0.94–3.12

0.06

Smoking

0.97

0.35–1.23

0.21

Systolic blood pressure

1.45

0.87–2.85

0.03*

Diastolic blood pressure

1.20

0.76–1.53

0.01*

Serum creatinine(mg/dl)

0.88

0.58–1.44

0.26

Protein-to-creatinine ratio(mg/g)

1.51

0.61–2.00

0.08

eGFR(ml/min)

1.27

0.82–2.61

0.10

rs1799983 genotype(GT)

1.78

1.18–3.24

0.01*

rs1800471 genotype (GC)

0.40

0.34–1.15

0.12

  1. BMI body mass index, FBG fasting blood glucose, PPG postprandial blood glucose, eGFR estimated glomerular filtration rate, OR odds ratio, CI confidence interval