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Table 7 Characteristics and clinical parameters of different eNOS genotypes

From: Role of eNOS and TGFβ1 gene polymorphisms in the development of diabetic nephropathy in type 2 diabetic patients in South Indian population

Clinical characteristics

eNOS GG

eNOS TT

P value

Age (years)

55.5 ± 0.61

55.1 ± 0.35

NS

Gender (male/female)

43/64

52/89

NS

BMI (kg/m2)

25.1 ± 1.11

24.9 ± 1.09

NS

Diabetes duration (years)

15.3 ± 0.4

12 ± 0.1

 < 0.001

Fasting blood glucose (mg/dL)

135.9 ± 0.66

141.8 ± 2.60

0.0007*

Post prandial glucose (mg/dL)

123.4 ± 1.48

125.8 ± 2.16

0.03*

HbA1c (%)

7.6 ± 2.2

8.6 ± 1.2

 < 0.05*

eGFR (ml/min)

73.5 ± 1.38

66.1 ± 2.1

0.03*

Protein-to-creatinine ratio (mg/g)

49.3 ± 2.4

62.3 ± 3.2

 < 0.001*

Systolic blood pressure (mmHg)

115 ± 0.80

125.8 ± 0.8

 < 0.001*

Diastolic blood pressure (mmHg)

78.7 ± 1.43

83.0 ± 4.12

0.01*

  1. Data are n, means ± SEM
  2. BMI body mass index, HbA1c glycosylated haemoglobin, eNOS endothelial nitric oxide, eGFR estimated glomerular filtration rate, NS non-significant
  3. *p < 0.05